Order and treatment record
Bring or send the signed order, diagnosis, intended dose, last injection or oral dose, next due date, initiation history, and prescriber contact details.
Abilify Maintena is a monthly aripiprazole injection for adults with schizophrenia and for maintenance treatment of bipolar I disorder on its own. A healthcare professional gives it into the shoulder or buttock muscle. The label allows two different start regimens: a one-day sequence with two injections and an oral dose, or one injection with 14 days of prescribed oral coverage. Your prescriber chooses the regimen after reviewing oral tolerability and other medicines. Ongoing visits review symptoms, movement effects, metabolic health and daily function as well as the next injection date.
Abilify Maintena is a long-acting aripiprazole injection for adults with schizophrenia and for maintenance treatment of bipolar I disorder on its own. A healthcare professional gives it into the shoulder or buttock muscle, usually once a month. The label says not to give a maintenance dose sooner than 26 days after the previous injection. Its role is ongoing treatment. It is not the same product as oral Abilify, Abilify Asimtufii, Aristada or Aristada Initio.
Aripiprazole acts at dopamine and serotonin receptors. Its effect is thought to involve partial activation of some receptors and blocking others. The exact way it produces clinical benefit is not fully known. The injection releases medicine over time, which changes the daily-pill routine but does not remove the need to review symptoms or side effects.
The clinician reviews the diagnosis, previous benefit, side effects and whether aripiprazole is tolerated by mouth. For someone who has never taken it, oral tolerability must be established first. A medication review also checks drugs that change aripiprazole levels, including certain antidepressants, antibiotics and seizure medicines. The long-lasting formulation makes this review important before committing to an injection.
Discuss what you want to improve and what makes daily tablets difficult. Include sleep, voices, mood stability, work and side effects. An injection is one treatment choice, not a judgement about how well you follow instructions.
One labelled option uses two separate Maintena injections and one oral aripiprazole dose in a day. Another uses one injection with 14 consecutive days of oral aripiprazole or the current oral antipsychotic. The prescriber selects the appropriate regimen and checks interactions.
Each administration record should show the exact dose, date and next due date. Psychiatric follow-up reviews whether the treatment still meets your goals. A community injection visit does not replace that review.
Bring the exact product name, prescribed strength, last injection date, oral medicine list and the responsible prescriber’s contact information. Include discharge notes, recent blood tests and any written start or restart plan. Tell the team about pregnancy, breastfeeding, allergies, seizures, fainting, substance use and new medicines or supplements. If a dose is delayed or records are unclear, contact the prescriber before travelling to an administration visit.
The boxed warning states that antipsychotics increase the risk of death in older adults with dementia-related psychosis. This medicine is not approved for that use. Weight gain, restlessness, injection-site pain and sedation are common effects in the schizophrenia studies. Monitoring includes weight, blood sugar, cholesterol, blood pressure and movement symptoms. Report new urges to gamble, shop, eat compulsively or engage in sexual activity. Aripiprazole can impair thinking or movement. Avoid driving until you know how it affects you. Seek emergency care for severe trouble breathing, throat or tongue swelling, loss of consciousness, or high fever with severe muscle stiffness and confusion. Contact the treating team promptly for new involuntary movements, severe restlessness, worsening psychosis, marked dizziness or troublesome injection-site symptoms. Do not wait for the next routine injection to report a serious concern.
If the second or third dose is late, the restart threshold differs from the fourth or later doses. More than five weeks after an early dose or more than six weeks after later maintenance can require a new initiation regimen. Give the team your actual injection dates. Do not decide that you can safely skip treatment because you still feel well.
Before an injection appointment, ask which clinic can accept the prescription, how the medicine will be obtained, and which costs belong to the medicine, administration and psychiatry follow-up. A benefits check, prior authorization and medicine delivery are different steps. Ask for the proposed cost before each step. Manufacturer assistance has its own eligibility rules. Office-visit coverage does not establish medication coverage, and a listed clinic does not establish that the product is stocked or can be given there today.
Nao Medical can coordinate psychiatric injection care with your prescribing psychiatrist. Share the current order, exact medicine, last dose date and treatment history through the confirmed clinical intake process. The clinicians review product-specific initiation or restart requirements and arrange medication delivery, administration and follow-up. Keep your existing treatment plan until the next appointment is agreed.
Abilify Maintena is a long-acting aripiprazole injection for adults with schizophrenia and for maintenance treatment of bipolar I disorder on its own. A healthcare professional gives it into the shoulder or buttock muscle, usually once a month. The label says not to give a maintenance dose sooner than 26 days after the previous injection. Its role is ongoing treatment. It is not the same product as oral Abilify, Abilify Asimtufii, Aristada or Aristada Initio.
The clinician reviews the diagnosis, previous benefit, side effects and whether aripiprazole is tolerated by mouth. For someone who has never taken it, oral tolerability must be established first. A medication review also checks drugs that change aripiprazole levels, including certain antidepressants, antibiotics and seizure medicines. The long-lasting formulation makes this review important before committing to an injection.
Discuss what you want to improve and what makes daily tablets difficult. Include sleep, voices, mood stability, work and side effects. An injection is one treatment choice, not a judgement about how well you follow instructions.
One labelled option uses two separate Maintena injections and one oral aripiprazole dose in a day. Another uses one injection with 14 consecutive days of oral aripiprazole or the current oral antipsychotic. The prescriber selects the appropriate regimen and checks interactions.
Each administration record should show the exact dose, date and next due date. Psychiatric follow-up reviews whether the treatment still meets your goals. A community injection visit does not replace that review.
If the second or third dose is late, the restart threshold differs from the fourth or later doses. More than five weeks after an early dose or more than six weeks after later maintenance can require a new initiation regimen. Give the team your actual injection dates. Do not decide that you can safely skip treatment because you still feel well.
The clinician reviews the diagnosis, previous benefit, side effects and whether aripiprazole is tolerated by mouth. For someone who has never taken it, oral tolerability must be established first. A medication review also checks drugs that change aripiprazole levels, including certain antidepressants, antibiotics and seizure medicines. The long-lasting formulation makes this review important before committing to an injection.
A switch needs the responsible psychiatrist's documented plan, not just an administration appointment. Review the exact current product, strength, last dose, response and tolerability. The new injection has its own indication, prior-treatment, loading or oral-coverage rules. Ask whether Nao provides the prescribing evaluation or accepts an outside order, and confirm delivery, the administering site and follow-up before changing treatment. Do not stop or convert medicines yourself.
Continuing antipsychotic care reviews symptoms, daily function, injection dates, movement symptoms, sedation, falls, weight, blood pressure and medicine-specific blood tests. Blood sugar/lipids, prolactin or heart-rhythm assessment may be relevant depending on the product and history. Ask the psychiatrist which tests are due and who reviews them. An administration-only visit does not replace that care. Report new involuntary movements, marked restlessness, fainting or troublesome injection-site changes promptly.
The reviewed current US prescribing information for Abilify Maintena does not specify a restricted REMS administration/distribution program. That does not remove the medicine’s prescribing, administration, initiation or monitoring requirements. Confirm the exact product and current FDA status with the treating clinician and dispensing service; a manufacturer access program is not itself an FDA REMS.
Have your insurance card ready when booking. Share member details through the clinic’s confirmed secure intake process. Check with the clinic and your insurer that the exact plan covers the clinician and requested service. Ask about visit charges, any separately billed tests or medicines, and any referral or authorization requirement. Coverage and your copay or deductible depend on the plan; request a written estimate if paying yourself.
No. The current label also allows a one-day initiation regimen. A single routine injection without the prescribed oral coverage or approved one-day regimen is a different situation. Ask the prescriber for the exact written plan.
No guarantee. Akathisia, a distressing urge to move, can occur with injected aripiprazole. Tell the clinician about past restlessness before starting and report new symptoms promptly. The injection continues releasing medicine over time.
The prepared 400 mg dose is 2 mL. The vial kit uses 1.9 mL of sterile water to prepare the suspension. That is different from the final volume injected. A healthcare professional prepares and gives this intramuscular medicine using the exact kit instructions. Do not use this volume to substitute another aripiprazole product or prepare an injection yourself.
Routine Maintena maintenance is monthly, and the label says no sooner than 26 days after the previous injection. Every three weeks is 21 days and falls outside that labeled maintenance interval. Contact the prescriber if symptoms return before the next dose or travel affects the appointment. The starting regimens and a missed-dose restart are separate decisions; do not shorten the interval yourself.
Its labeled storage is at room temperature rather than in a refrigerator. The prefilled dual-chamber syringe is stored below 30°C (86°F), protected from light in its original package, and must not be frozen. The vial is stored at 25°C (77°F), with permitted excursions from 15°C to 30°C. Ask the dispensing pharmacy about the exact kit and any temperature exposure before use.
Medicine remains after the monthly treatment interval ends. After repeated gluteal doses, the label reports an average terminal half-life of about 30 days for 300 mg and 46.5 days for 400 mg. A half-life is the time for a drug level to fall by half, not the time until it is completely gone. Several half-lives can pass before most medicine clears. Side effects, interactions and switching plans therefore need review even after injections stop.
The label does not give one day when every patient will feel better. The prescribed start regimen provides medication coverage while the injection begins releasing aripiprazole. Stable drug concentrations are reached by the fourth dose, but concentration and symptom improvement are different measures. Review sleep, voices, mood and daily function with the psychiatrist during treatment. Report worsening symptoms promptly instead of waiting for several injections to pass.
Medicare can cover clinician-administered injections under Part B when its coverage conditions are met. That is not a coverage guarantee for your exact prescription, diagnosis or site. Ask the provider and plan which benefit will be billed and whether the provider accepts assignment. Check approvals and patient costs for the medicine and administration. If the drug is handled through Part D, check the plan’s formulary and pharmacy requirements.
Bring or send the signed order, diagnosis, intended dose, last injection or oral dose, next due date, initiation history, and prescriber contact details.
Include current medicines, allergies, prior adverse effects, pregnancy or breastfeeding considerations, recent hospitalization records, and relevant laboratory or monitoring results.
Share insurance cards, the specialty pharmacy or distributor if known, prior authorization status, and the intended patient-specific delivery destination.
Wait for the care team to confirm order acceptance, medication arrival, the eligible clinic, trained staff, and appointment time before traveling.
Bronx
932 E 174th St, Bronx, NY 10460
A nearby Nao Medical access point for evaluation, records coordination, and follow-up planning for patients in West Farms, Crotona Park East, and nearby Bronx neighborhoods. The administration clinic will be confirmed separately by the care team.
Queens
37-15 23rd Ave, Astoria, NY 11105
A nearby Nao Medical access point for evaluation, records coordination, and follow-up planning for patients in Astoria, Ditmars, East Elmhurst, and nearby Queens neighborhoods. The administration clinic will be confirmed separately by the care team.
Bronx
2063A Bartow Ave, Bronx, NY 10475
A nearby Nao Medical access point for evaluation, records coordination, and follow-up planning for patients in Co-op City, Pelham Bay, Baychester, and nearby Bronx neighborhoods. The administration clinic will be confirmed separately by the care team.
Brooklyn
341 Eastern Pkwy, Brooklyn, NY 11216
A nearby Nao Medical access point for evaluation, records coordination, and follow-up planning for patients in Crown Heights, Prospect Heights, and nearby Brooklyn neighborhoods. The administration clinic will be confirmed separately by the care team.
Long Island
232 W Old Country Rd, Hicksville, NY 11801
A nearby Nao Medical access point for evaluation, records coordination, and follow-up planning for patients in Hicksville, Plainview, Bethpage, and nearby Nassau County communities. The administration clinic will be confirmed separately by the care team.
Queens
80-10 Northern Blvd, Jackson Heights, NY 11372
A nearby Nao Medical access point for evaluation, records coordination, and follow-up planning for patients in Jackson Heights, Elmhurst, Corona, and nearby Queens neighborhoods. The administration clinic will be confirmed separately by the care team.
Queens
90-18 Sutphin Blvd, Jamaica, NY 11435
A nearby Nao Medical access point for evaluation, records coordination, and follow-up planning for patients in Jamaica, Briarwood, Richmond Hill, and nearby Queens neighborhoods. The administration clinic will be confirmed separately by the care team.
Queens
30-07 36th Ave, Astoria, NY 11106
A nearby Nao Medical access point for evaluation, records coordination, and follow-up planning for patients in Long Island City, Astoria, Sunnyside, and nearby Queens neighborhoods. The administration clinic will be confirmed separately by the care team.
Long Island
135 Mineola Blvd, Mineola, NY 11501
A nearby Nao Medical access point for evaluation, records coordination, and follow-up planning for patients in Mineola, Garden City, Westbury, and nearby Nassau County communities. The administration clinic will be confirmed separately by the care team.
Manhattan
259 1st Ave, New York, NY 10003
A nearby Nao Medical access point for evaluation, records coordination, and follow-up planning for patients in StuyTown, East Village, Gramercy, and nearby Manhattan neighborhoods. The administration clinic will be confirmed separately by the care team.
Brooklyn
308 Graham Ave, Brooklyn, NY 11211
A nearby Nao Medical access point for evaluation, records coordination, and follow-up planning for patients in Williamsburg, Greenpoint, Bushwick, and nearby Brooklyn neighborhoods. The administration clinic will be confirmed separately by the care team.
Official sources checked August 1, 2026. The DailyMed label shown above has an effective date of 2026-03-24 and identifies prescribing-information revision 03/2025. Questions or corrections about this medical information can be sent to service@naomedical.com.
Content was updated August 4, 2026 using the sources cited above. Medical guidance, prescribing information, medication availability, and insurance rules can change. A licensed clinician must confirm current information and determine each patient's eligibility, testing, treatment, administration setting, and follow-up. Call 911 for a medical emergency. Contact Nao Medical with a question or correction.