The referring HIV clinician stays central
The clearest intake starts with the office managing the HIV regimen, because the injection site should not have to guess at candidacy, dosing, or the product plan.
A useful referral includes the responsible HIV clinician, eligibility decision, current regimen, resistance and viral-load records, prescription, target dates and laboratory plan. Confirm how medication is obtained and who verifies receipt. If an alternative site of care gives the injections, it should return administration dates and report missed visits or reactions to the HIV clinician. It does not take over regimen management simply by administering a dose. Keep current ART until the clinician's transition instructions take effect. Before attending, confirm authorization, supply and the appointment rather than assuming a submitted referral has completed every step.
Cabenuva is a complete injectable regimen of cabotegravir and rilpivirine used to replace an existing HIV-1 treatment regimen in eligible people whose virus is already suppressed. It is HIV treatment, not PrEP. A professional gives two injections into gluteal muscles at scheduled visits. Fewer daily pills can be helpful, but maintaining suppression still depends on attendance, laboratory monitoring and an uninterrupted treatment plan if injections stop.
The labeled indication includes adults and adolescents aged 12 or older who weigh at least 35 kg and have HIV RNA below 50 copies/mL on a stable regimen. It also requires no history of treatment failure and no known or suspected resistance to either medicine. The HIV clinician reviews prior regimens and resistance records, rather than relying on one recent viral-load result. Hepatitis B, pregnancy, interacting medicines, liver disease and ability to attend visits also affect the decision. Cabenuva does not treat hepatitis B.
The clinician responsible for HIV care confirms suppression, treatment history and suitability. Do not stop current tablets while a referral, authorization or delivery is pending.
Monthly and every-two-month injection schedules are available. An oral lead-in with both medicines is optional. The every-two-month pathway begins with two initiation visits one month apart before moving to the continuing calendar.
A referring HIV office and an alternative site of care may have different roles. Confirm the prescription, supply route, target date, labs, injection record and where urgent questions go. The administration site does not replace the HIV clinician who manages the regimen.
Arrange viral-load testing after the change and continuing treatment-safety review. The team needs a plan for travel, delays, side effects and return to another suppressive regimen if needed.
Bring a complete medicine list, prior ART and resistance records, recent viral-load results and any hepatitis B history. Include acid-reducing medicines if oral rilpivirine is considered, because tablet interactions differ from injection interactions. Confirm who orders and receives labs, who authorizes oral coverage for a missed visit and who can reschedule you. Book the next target date before leaving when possible.
Pain or swelling at injection sites is common. Severe allergy, jaundice or a significant mood change needs prompt assessment. Rare serious reactions can occur shortly after rilpivirine injection, so the administration team follows the label’s observation instructions. Report breathing difficulty, chest symptoms or fainting immediately. Medicines for seizures, TB and other conditions, including some supplements, can make Cabenuva unsuitable; do not start them without coordinated review.
The schedule is monthly or every two calendar months, not a freely interchangeable eight-week interval. Tell both the HIV clinician and administration team immediately if a visit may be more than seven days late. Oral coverage or a different injection restart may be needed. If Cabenuva stops, another fully suppressive regimen must start on the label’s timeline: no later than one month after the final monthly injections or two months after the final every-two-month injections. Viral-load follow-up remains necessary.
Ask about approval for both injectable drugs, administration fees, laboratory charges and the exact site. A locator entry, referral or authorization alone does not show that medication has arrived or an appointment is booked. Confirm these steps while continuing the agreed HIV regimen. Contact the responsible HIV clinician for treatment decisions, including any detectable viral-load result after switching.
Bring a complete medicine list, prior ART and resistance records, recent viral-load results and any hepatitis B history. Include acid-reducing medicines if oral rilpivirine is considered, because tablet interactions differ from injection interactions. Confirm who orders and receives labs, who authorizes oral coverage for a missed visit and who can reschedule you. Book the next target date before leaving when possible.
The clinician responsible for HIV care confirms suppression, treatment history and suitability. Do not stop current tablets while a referral, authorization or delivery is pending.
Monthly and every-two-month injection schedules are available. An oral lead-in with both medicines is optional. The every-two-month pathway begins with two initiation visits one month apart before moving to the continuing calendar.
A referring HIV office and an alternative site of care may have different roles. Confirm the prescription, supply route, target date, labs, injection record and where urgent questions go. The administration site does not replace the HIV clinician who manages the regimen.
Arrange viral-load testing after the change and continuing treatment-safety review. The team needs a plan for travel, delays, side effects and return to another suppressive regimen if needed.
Ask intake whether preliminary scheduling can begin while records are being obtained and which items must arrive before clinical acceptance. Once intake is complete, the responsible prescriber reviews eligibility, issues the exact order and confirms any start/restart plan. Insurance, medicine sourcing, site acceptance and an administration appointment are separate steps. Do not assume the first intake visit includes an injection.
Have your insurance card ready when booking. Share member details through the clinic’s confirmed secure intake process. Check with the clinic and your insurer that the exact plan covers the clinician and requested service. Ask about visit charges, any separately billed tests or medicines, and any referral or authorization requirement. Coverage and your copay or deductible depend on the plan; request a written estimate if paying yourself.
Call the HIV clinician and administration site with the exact dates. A delay beyond the permitted window may require oral therapy and clinical reassessment. Never assume the long-lasting medicine makes a gap harmless.
One result requires interpretation with earlier results, timing, adherence and possible interactions. Your HIV clinician decides when to repeat testing and whether resistance assessment or a treatment change is needed. A forum cannot establish that your result is harmless.
Discuss soreness, prior reactions, travel and the need to attend every appointment. Confirm the expected visit process with the site. Neither a standard amount of time off nor a promise of painless injections applies to everyone.
Weight increase has been reported with cabotegravir/rilpivirine. In the pooled FLAIR and ATLAS trials, the median gain at week 48 was 1.5 kg with the injectable regimen. The current-treatment groups had a median gain of 1.0 kg. That group result does not predict your change or show that every weight change is caused by Cabenuva. Discuss the trend, other medicines, diet, symptoms and metabolic health with the HIV clinician. Do not stop a suppressive regimen on your own. The clinician can assess causes and, if needed, plan another complete regimen.
Cabotegravir blocks HIV integrase and rilpivirine blocks reverse transcriptase. Together they keep HIV from multiplying. The medicines remain in the body for months after the last injections. That persistence makes missed visits and discontinuation important: falling drug levels can allow viral rebound and resistance if a fully suppressive regimen is not maintained.
The clearest intake starts with the office managing the HIV regimen, because the injection site should not have to guess at candidacy, dosing, or the product plan.
Insurance, specialty pharmacy details, and whether the medication is moving under a medical or pharmacy benefit can change how quickly the first appointment can be confirmed.
The first injection site should also be realistic for the ongoing cadence, because changing locations later can complicate the administration path.
ViiVConnect can review coverage, explain savings or support options, and help patients understand the administration path. Access Coordinators can be reached at 1-844-588-3288, Monday through Friday, 8 AM to 8 PM ET.
Bronx
932 E 174th St, Bronx, NY 10460
A Bronx administration site for referral-based CABENUVA injections, repeat monthly or every-other-month visits, and coverage coordination for patients in West Farms, Crotona Park East, and nearby Bronx neighborhoods.
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37-15 23rd Ave, Astoria, NY 11105
A Queens administration site for referral-based CABENUVA injections, repeat monthly or every-other-month visits, and coverage coordination for patients in Astoria, Ditmars, East Elmhurst, and nearby Queens neighborhoods.
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Bronx
2063A Bartow Ave, Bronx, NY 10475
A Bronx administration site for referral-based CABENUVA injections, repeat monthly or every-other-month visits, and coverage coordination for patients in Co-op City, Pelham Bay, Baychester, and nearby Bronx neighborhoods.
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Brooklyn
341 Eastern Pkwy, Brooklyn, NY 11216
A Brooklyn administration site for referral-based CABENUVA injections, repeat monthly or every-other-month visits, and coverage coordination for patients in Crown Heights, Prospect Heights, and nearby Brooklyn neighborhoods.
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Long Island
232 W Old Country Rd, Hicksville, NY 11801
A Long Island administration site for referral-based CABENUVA injections, repeat monthly or every-other-month visits, and coverage coordination for patients in Hicksville, Plainview, Bethpage, and nearby Nassau County communities.
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Queens
80-10 Northern Blvd, Jackson Heights, NY 11372
A Queens administration site for referral-based CABENUVA injections, repeat monthly or every-other-month visits, and coverage coordination for patients in Jackson Heights, Elmhurst, Corona, and nearby Queens neighborhoods.
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Queens
90-18 Sutphin Blvd, Jamaica, NY 11435
A Queens administration site for referral-based CABENUVA injections, repeat monthly or every-other-month visits, and coverage coordination for patients in Jamaica, Briarwood, Richmond Hill, and nearby Queens neighborhoods.
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Queens
30-07 36th Ave, Astoria, NY 11106
A Queens administration site for referral-based CABENUVA injections, repeat monthly or every-other-month visits, and coverage coordination for patients in Long Island City, Astoria, Sunnyside, and nearby Queens neighborhoods.
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Long Island
135 Mineola Blvd, Mineola, NY 11501
A Long Island administration site for referral-based CABENUVA injections, repeat monthly or every-other-month visits, and coverage coordination for patients in Mineola, Garden City, Westbury, and nearby Nassau County communities.
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Manhattan
259 1st Ave, New York, NY 10003
A Manhattan administration site for referral-based CABENUVA injections, repeat monthly or every-other-month visits, and coverage coordination for patients in StuyTown, East Village, Gramercy, and nearby Manhattan neighborhoods.
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Brooklyn
308 Graham Ave, Brooklyn, NY 11211
A Brooklyn administration site for referral-based CABENUVA injections, repeat monthly or every-other-month visits, and coverage coordination for patients in Williamsburg, Greenpoint, Bushwick, and nearby Brooklyn neighborhoods.
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