Metformin
The international guideline supports considering metformin for metabolic and anthropometric outcomes in adults with PCOS and higher BMI. It is not an FDA-approved weight-loss drug.
PMOS is a multisystem endocrine and metabolic condition. Care should not be reduced to a number on the scale or an assumption about ovarian cysts.
Review weight trajectory, prior programs, nutrition patterns, movement, sleep, stress, medicines, and what has or has not been sustainable.
Review blood pressure, glucose or diabetes risk, lipids, liver-health questions, family history, and other weight-related conditions.
Discuss menstrual patterns, contraception, pregnancy timing, infertility care, and medicines that may conflict with those goals.
Review the existing diagnosis and current symptoms; arrange appropriate testing or referral when the diagnosis or scope is uncertain.
Screen for anxiety, depression, body-image distress, disordered eating, and support needs without assuming that every patient has the same experience.
Choose monitoring, nutrition, activity, medication, primary care, women's health, and specialist coordination that can continue beyond the first prescription.
The right plan depends on the clinical target. A medicine used for metabolic features of PMOS is not automatically a substitute for an FDA-approved chronic weight-management medicine.
The international guideline supports considering metformin for metabolic and anthropometric outcomes in adults with PCOS and higher BMI. It is not an FDA-approved weight-loss drug.
The guideline says GLP-1 receptor agonists may be considered for higher weight under general obesity rules. Wegovy and Saxenda have weight-management indications; product and eligibility matter.
Zepbound is a dual GIP and GLP-1 receptor agonist approved for chronic weight management in eligible adults, not specifically for PMOS or PCOS.
Lifestyle support remains part of care, while goals should be individualized, respectful, and valuable even when weight does not change quickly.
Irregular cycles, contraception, abnormal bleeding, pregnancy goals, and other gynecologic concerns may need a parallel women's-health plan.
Complex endocrine disease, infertility treatment, eating disorders, pregnancy, or another concern may need endocrinology, gynecology, reproductive medicine, or behavioral-health care.
Share the diagnosis, weight and treatment history, current medicines, symptoms, reproductive goals, and the outcome that matters most.
The clinician reviews health history, vital signs, relevant labs, contraindications, and whether another service or specialist should be involved.
If medication is appropriate, the team reviews the labeled indication, health-plan requirements, pharmacy access, and a realistic follow-up schedule.
Follow-up reviews response, side effects, nutrition, hydration, muscle-preserving activity, metabolic markers, menstrual or pregnancy changes, and whether the plan should continue.
Book the existing medical weight-loss evaluation. The care team will confirm whether the first visit is virtual or in person and whether women's-health or specialist coordination is also needed.
Bronx
932 E 174th St, Bronx, NY 10460
Start a condition-aware weight-management evaluation and bring prior PMOS or PCOS records when available. The scheduling team will confirm the right visit type and current clinic availability.
Queens
37-15 23rd Ave, Astoria, NY 11105
Start a condition-aware weight-management evaluation and bring prior PMOS or PCOS records when available. The scheduling team will confirm the right visit type and current clinic availability.
Bronx
2063A Bartow Ave, Bronx, NY 10475
Start a condition-aware weight-management evaluation and bring prior PMOS or PCOS records when available. The scheduling team will confirm the right visit type and current clinic availability.
Brooklyn
341 Eastern Pkwy, Brooklyn, NY 11216
Start a condition-aware weight-management evaluation and bring prior PMOS or PCOS records when available. The scheduling team will confirm the right visit type and current clinic availability.
Long Island
232 W Old Country Rd, Hicksville, NY 11801
Start a condition-aware weight-management evaluation and bring prior PMOS or PCOS records when available. The scheduling team will confirm the right visit type and current clinic availability.
Queens
80-10 Northern Blvd, Jackson Heights, NY 11372
Start a condition-aware weight-management evaluation and bring prior PMOS or PCOS records when available. The scheduling team will confirm the right visit type and current clinic availability.
Queens
90-18 Sutphin Blvd, Jamaica, NY 11435
Start a condition-aware weight-management evaluation and bring prior PMOS or PCOS records when available. The scheduling team will confirm the right visit type and current clinic availability.
Queens
30-07 36th Ave, Astoria, NY 11106
Start a condition-aware weight-management evaluation and bring prior PMOS or PCOS records when available. The scheduling team will confirm the right visit type and current clinic availability.
Long Island
135 Mineola Blvd, Mineola, NY 11501
Start a condition-aware weight-management evaluation and bring prior PMOS or PCOS records when available. The scheduling team will confirm the right visit type and current clinic availability.
Manhattan
259 1st Ave, New York, NY 10003
Start a condition-aware weight-management evaluation and bring prior PMOS or PCOS records when available. The scheduling team will confirm the right visit type and current clinic availability.
Brooklyn
308 Graham Ave, Brooklyn, NY 11211
Start a condition-aware weight-management evaluation and bring prior PMOS or PCOS records when available. The scheduling team will confirm the right visit type and current clinic availability.
Review general obesity-treatment criteria, safety, and whether a labeled product fits.
Compare different medication roles for metabolic and weight-management goals.
Coordinate contraception, preconception timing, and treatment transitions.
Prepare for benefit checks, prior authorization, and pharmacy requirements.
Review Nao Medical's broader evaluation and monitoring program.
Current guidelines and prescribing information define the evidence, approved uses, and safety boundaries. They do not determine whether a medicine is appropriate for an individual patient.
General information only. The information here is not medical advice and does not replace diagnosis, treatment, or guidance from a licensed clinician.
Content was updated August 2, 2026 from the cited sources and Nao Medical's current service information. Medical guidance, prescribing information, medication availability, and insurance rules can change. A licensed clinician must confirm current information and determine each patient's eligibility, testing, treatment, administration setting, and follow-up. Call 911 for a medical emergency. Contact Nao Medical with a question or correction.