(917) 310-3371
Original result and prior history
Bring the TB blood or skin-test result, date, measurement when relevant, prior chest imaging, exposure history, BCG history, and any prior latent or active TB treatment.
Treatment starts only after active TB is excluded
PPD and TB testing covers screening, test selection, timing, readings, and forms. Latent TB treatment begins after a positive result needs clinical follow-through.
What must be reviewed before preventive treatment
The clinician confirms that the result represents TB infection, looks for active disease, and selects a regimen that is safe with the rest of the patient's care.
Active-disease exclusion
Symptoms, examination, and chest radiography help distinguish latent infection from pulmonary TB disease. Sputum testing is required when active disease is possible.
Progression risk
Recent exposure, HIV or other immune suppression, young age, diabetes, and other factors can increase the priority for treatment and specialist or public-health coordination.
Interaction and liver review
Rifampin and rifapentine interact with many medicines, including some HIV treatments, hormonal contraception, anticoagulants, methadone, and other drugs. Liver risk and pregnancy also affect the plan.
From a positive test to documented completion
Treatment is preventive and often starts when a person feels well. A clear regimen, interaction plan, and monthly contact improve the chance of safe completion.
1. Review the positive test
Confirm the type and date of test, TB exposure and risk factors, symptoms, BCG history, prior treatment, immune status, and reason the test was ordered.
2. Exclude active TB disease
Complete a symptom review and chest radiograph. Arrange sputum testing, infection-control precautions, specialist consultation, and NYC Health Department coordination when active TB is possible.
3. Select the regimen
CDC prefers three- or four-month rifamycin-based treatment when appropriate, but age, pregnancy, HIV medicines, presumed drug resistance, interactions, and tolerability can require another regimen.
4. Establish laboratory and interaction monitoring
Baseline liver tests are not routine for everyone, but CDC recommends them for selected risks, including HIV, pregnancy or recent postpartum status, liver disease, regular alcohol or injection-drug use, and other chronic-liver risks.
5. Assess progress at least monthly
Review adherence, symptoms of TB disease, medication reactions, new medicines, and missed doses. Order repeat laboratory tests when baseline results or clinical risk requires them.
6. Issue completion documentation
Keep the original test, chest-radiograph result, medication names and doses, treatment dates, and duration. Most people remain test-positive after successful treatment, so repeat TB tests usually do not prove completion.
Medication and active-TB warning signs
The clinician should give written instructions for normal effects, possible toxicity, and symptoms that require immediate evaluation.
Possible active TB
A cough lasting three weeks or longer, coughing blood or sputum, chest pain, fever, night sweats, weight loss, fatigue, or poor appetite requires prompt active-TB assessment.
Liver injury
Stop the medication and contact the clinician immediately for unexplained loss of appetite, persistent nausea or vomiting, dark or brown urine, pale stool, abdominal pain, or yellow skin or eyes.
Other serious reactions
Persistent numbness or tingling, easy bruising or bleeding, vision change, severe weakness, fever, or rash requires prompt review.
Rifamycin interactions
Rifampin and rifapentine can lower or raise the effect of other medicines. Do not start them until every prescription, supplement, contraceptive, HIV medicine, and substance-use treatment is reviewed.
Possible active TB needs a different level of care
Call before arriving at a routine clinic if you have a prolonged cough, coughing blood, fever, night sweats, weight loss, or known exposure to active TB. NYC providers must promptly report suspected or confirmed active TB. Call 911 for severe breathing trouble, significant coughing of blood, fainting, or another medical emergency.
Testing, imaging, medication, follow-up, and public services may have different coverage
A positive-test follow-up can involve a medical evaluation, chest radiograph, laboratory tests, medication, monthly visits, and specialist or public-health services. Confirm what is in network and what is billed separately.
NYC Health Department Chest Centers provide TB services and medicines without charge. Referral can be appropriate when cost, complexity, suspected active disease, drug interactions, or public-health follow-up makes that the best pathway.
What to bring
Complete records reduce delays, duplicate testing, and avoidable medication errors.
- Original TB blood or skin-test report, including the date and skin-test measurement when available.
- Prior chest imaging, prior TB treatment records, and known exposure information.
- Symptoms, immune conditions, HIV status, pregnancy or postpartum status, and liver history.
- Every medication, supplement, contraceptive, anticoagulant, seizure medicine, and substance-use treatment.
- Employer, school, immigration, or program documentation requirements and deadline.
Evaluation and coordination locations
Call first to confirm the correct visit, clinician, testing, medication, infection-control, and site-capability requirements. A location card is not a promise of medication stock or same-day administration.
Bronx
174th Street
932 E 174th St, Bronx, NY 10460
This clinic can be a starting point for positive-test review and treatment coordination. Call first to confirm imaging, laboratory, clinician, infection-control, and public-health needs; the card does not confirm on-site TB treatment capability. Serves West Farms, Crotona Park East, and nearby Bronx neighborhoods.
Queens
Astoria
37-15 23rd Ave, Astoria, NY 11105
This clinic can be a starting point for positive-test review and treatment coordination. Call first to confirm imaging, laboratory, clinician, infection-control, and public-health needs; the card does not confirm on-site TB treatment capability. Serves Astoria, Ditmars, East Elmhurst, and nearby Queens neighborhoods.
Bronx
Bartow Mall
2063A Bartow Ave, Bronx, NY 10475
This clinic can be a starting point for positive-test review and treatment coordination. Call first to confirm imaging, laboratory, clinician, infection-control, and public-health needs; the card does not confirm on-site TB treatment capability. Serves Co-op City, Pelham Bay, Baychester, and nearby Bronx neighborhoods.
Brooklyn
Crown Heights
341 Eastern Pkwy, Brooklyn, NY 11216
This clinic can be a starting point for positive-test review and treatment coordination. Call first to confirm imaging, laboratory, clinician, infection-control, and public-health needs; the card does not confirm on-site TB treatment capability. Serves Crown Heights, Prospect Heights, and nearby Brooklyn neighborhoods.
Long Island
Hicksville
232 W Old Country Rd, Hicksville, NY 11801
This clinic can be a starting point for positive-test review and treatment coordination. Call first to confirm imaging, laboratory, clinician, infection-control, and public-health needs; the card does not confirm on-site TB treatment capability. Serves Hicksville, Plainview, Bethpage, and nearby Nassau County communities.
Queens
Jackson Heights
80-10 Northern Blvd, Jackson Heights, NY 11372
This clinic can be a starting point for positive-test review and treatment coordination. Call first to confirm imaging, laboratory, clinician, infection-control, and public-health needs; the card does not confirm on-site TB treatment capability. Serves Jackson Heights, Elmhurst, Corona, and nearby Queens neighborhoods.
Queens
Jamaica
90-18 Sutphin Blvd, Jamaica, NY 11435
This clinic can be a starting point for positive-test review and treatment coordination. Call first to confirm imaging, laboratory, clinician, infection-control, and public-health needs; the card does not confirm on-site TB treatment capability. Serves Jamaica, Briarwood, Richmond Hill, and nearby Queens neighborhoods.
Queens
Long Island City
30-07 36th Ave, Astoria, NY 11106
This clinic can be a starting point for positive-test review and treatment coordination. Call first to confirm imaging, laboratory, clinician, infection-control, and public-health needs; the card does not confirm on-site TB treatment capability. Serves Long Island City, Astoria, Sunnyside, and nearby Queens neighborhoods.
Long Island
Mineola
135 Mineola Blvd, Mineola, NY 11501
This clinic can be a starting point for positive-test review and treatment coordination. Call first to confirm imaging, laboratory, clinician, infection-control, and public-health needs; the card does not confirm on-site TB treatment capability. Serves Mineola, Garden City, Westbury, and nearby Nassau County communities.
Manhattan
StuyTown
259 1st Ave, New York, NY 10003
This clinic can be a starting point for positive-test review and treatment coordination. Call first to confirm imaging, laboratory, clinician, infection-control, and public-health needs; the card does not confirm on-site TB treatment capability. Serves StuyTown, the East Village, Gramercy, and nearby Manhattan neighborhoods.
Brooklyn
Williamsburg
308 Graham Ave, Brooklyn, NY 11211
This clinic can be a starting point for positive-test review and treatment coordination. Call first to confirm imaging, laboratory, clinician, infection-control, and public-health needs; the card does not confirm on-site TB treatment capability. Serves Williamsburg, Greenpoint, Bushwick, and nearby Brooklyn neighborhoods.
Patient questions
Is latent TB contagious?
No. People with latent, or inactive, TB do not have symptoms of TB disease and cannot spread TB to others. Active TB disease must still be excluded before preventive treatment begins.
Does a positive TB test prove active TB disease?
No. A positive blood or skin test usually means TB infection. A medical evaluation and chest radiograph are needed, and sputum testing may be required when active disease is possible.
How long does latent TB treatment take?
Recommended regimens can last three, four, six, or nine months. CDC preferentially recommends short-course rifamycin-based regimens when they are clinically appropriate.
Do I need liver tests before treatment?
Not everyone does. CDC recommends baseline liver testing for selected risks, including HIV, pregnancy or the first three months postpartum, liver disease, regular alcohol or injection-drug use, and other chronic-liver risks.
How often are follow-up visits?
CDC advises assessment at least monthly for adherence, symptoms of TB disease, and medication reactions. Laboratory testing is individualized.
Will my TB test become negative after treatment?
Usually not. Most people remain positive after treatment. Completion is documented with the original test, chest-radiograph result, medication and dose, and treatment duration.
What should I do if I miss doses?
Contact the treating clinician. Whether the regimen can continue or needs extension or restart depends on the medicine, number and timing of missed doses, and clinical circumstances.
When should I call before coming to the clinic?
Call first if you have a cough lasting three weeks or longer, coughing blood or sputum, chest pain, fever, night sweats, weight loss, or a known active-TB exposure. The team may direct you to a setting with appropriate airborne precautions.
Clinical and public-health sources
These official sources were checked on August 1, 2026. They support the general medical information and do not replace an individual evaluation.
Centers for Disease Control and Prevention
Treatment for latent tuberculosis infection
Active-disease exclusion, preferred short-course regimens, interactions, monthly assessment, laboratory risk factors, and completion documentation.
Centers for Disease Control and Prevention
Clinical and laboratory diagnosis for tuberculosis
Medical evaluation after a positive test, chest radiography, and sputum testing when active TB is possible.
Centers for Disease Control and Prevention
Adverse events during TB treatment
Medication interaction review, monthly monitoring, and warning symptoms that require prompt clinical review.
Centers for Disease Control and Prevention
Signs and symptoms of tuberculosis
Symptoms that can indicate active TB rather than latent infection.
New York City Department of Health and Mental Hygiene
Latent TB infection action kit
NYC screening, diagnosis, treatment, patient education, and completion resources.
New York City Department of Health and Mental Hygiene
Tuberculosis provider resources
NYC Chest Center referrals, provider consultation, reporting, and no-cost public services.
Publication remains blocked until a named clinical reviewer verifies current guidance, medication labeling, emergency instructions, and Nao Medical's exact care boundary.
Start with the right visit
This clinic can be a starting point for positive-test review and treatment coordination. Call first to confirm imaging, laboratory, clinician, infection-control, and public-health needs; the card does not confirm on-site TB treatment capability.
Health information notice
General information only. This page is not medical advice and does not replace diagnosis, treatment, or guidance from a licensed clinician.
Content was updated August 1, 2026 from the sources cited on this page. Medical guidance, prescribing information, medication availability, and insurance rules can change. A licensed clinician must confirm current information and determine each patient's eligibility, testing, treatment, administration setting, and follow-up. Call 911 for a medical emergency. Contact Nao Medical with a question or correction.