YEZTUGO is the twice-yearly lenacapavir PrEP option for people who want the longest dosing interval currently available, but the access path is still operationally heavier than a same-day pill pickup. Launch-ready care means the site, the medication-sourcing path, the HIV testing workflow, and the follow-up cadence all have to be lined up.
YEZTUGO is given as two subcutaneous injections every 6 months after starter dosing. On day 1, the patient receives two oral tablets and two injections in a medical setting. On day 2, two more oral tablets are taken at home. HIV testing is required before starting and before each injection visit.
Coverage support for YEZTUGO is still evolving. Official patient resources point patients to Gilead Advancing Access for benefits investigation, prior-authorization support, co-pay help for eligible commercially insured patients, and medication-assistance pathways for some uninsured patients. NYC guidance also notes that insurance policies are still changing and coverage can vary by payer.
Nao Medical is building a YEZTUGO launch-readiness lane for twice-yearly PrEP access, coverage support, and site planning across NYC and Long Island. These pages are written to explain the operational path clearly without pretending every location is already live for YEZTUGO administration today.
This lane is for people interested in YEZTUGO and the teams planning how it could go live safely and credibly across the Nao network.
YEZTUGO is the longest-acting PrEP option available, but it still depends on HIV testing, a clinical administration setting, medication access, and reliable follow-up.
Launch readiness means the site can really handle testing, procurement, storage, scheduling, billing, and the six-month follow-up cycle before it is marketed as active.
A truthful planned-site footprint helps patients and staff understand where the rollout is most likely to make sense once operations turn on.
YEZTUGO is given as two subcutaneous injections every 6 months after starter dosing. On day 1, the patient receives two oral tablets and two injections in a medical setting. On day 2, two more oral tablets are taken at home. HIV testing is required before starting and before each injection visit.
Launch readiness for YEZTUGO means more than writing a page or placing the drug on a list. Sites need procurement and specialty-pharmacy routing, staff training on subcutaneous administration, storage and handling workflow, scheduling logic for six-month follow-up, HIV testing workflow, billing setup, and a clear plan for delayed injections.
Gilead Advancing Access can help with benefits investigations, prior authorization, co-pay program enrollment for eligible commercially insured patients, and medication-assistance pathways. The program can be reached at 1-800-226-2056.
These are the locations that fit the rollout conversation once YEZTUGO operations are live. Each local page explains readiness and expectations rather than implying universal immediate availability.
Bronx
932 E 174th St, Bronx, NY 10460
A Bronx site planned for YEZTUGO administration once operations go live, serving patients in West Farms, Crotona Park East, and nearby Bronx neighborhoods with twice-yearly PrEP planning and six-month follow-up.
View YEZTUGO site page Get directions
Queens
37-15 23rd Ave, Astoria, NY 11105
A Queens site planned for YEZTUGO administration once operations go live, serving patients in Astoria, Ditmars, East Elmhurst, and nearby Queens neighborhoods with twice-yearly PrEP planning and six-month follow-up.
View YEZTUGO site page Get directions
Bronx
2063A Bartow Ave, Bronx, NY 10475
A Bronx site planned for YEZTUGO administration once operations go live, serving patients in Co-op City, Pelham Bay, Baychester, and nearby Bronx neighborhoods with twice-yearly PrEP planning and six-month follow-up.
View YEZTUGO site page Get directions
Brooklyn
341 Eastern Pkwy, Brooklyn, NY 11216
A Brooklyn site planned for YEZTUGO administration once operations go live, serving patients in Crown Heights, Prospect Heights, and nearby Brooklyn neighborhoods with twice-yearly PrEP planning and six-month follow-up.
View YEZTUGO site page Get directions
Long Island
232 W Old Country Rd, Hicksville, NY 11801
A Long Island site planned for YEZTUGO administration once operations go live, serving patients in Hicksville, Plainview, Bethpage, and nearby Nassau County communities with twice-yearly PrEP planning and six-month follow-up.
View YEZTUGO site page Get directions
Queens
80-10 Northern Blvd, Jackson Heights, NY 11372
A Queens site planned for YEZTUGO administration once operations go live, serving patients in Jackson Heights, Elmhurst, Corona, and nearby Queens neighborhoods with twice-yearly PrEP planning and six-month follow-up.
View YEZTUGO site page Get directions
Queens
90-18 Sutphin Blvd, Jamaica, NY 11435
A Queens site planned for YEZTUGO administration once operations go live, serving patients in Jamaica, Briarwood, Richmond Hill, and nearby Queens neighborhoods with twice-yearly PrEP planning and six-month follow-up.
View YEZTUGO site page Get directions
Queens
30-07 36th Ave, Astoria, NY 11106
A Queens site planned for YEZTUGO administration once operations go live, serving patients in Long Island City, Astoria, Sunnyside, and nearby Queens neighborhoods with twice-yearly PrEP planning and six-month follow-up.
View YEZTUGO site page Get directions
Long Island
135 Mineola Blvd, Mineola, NY 11501
A Long Island site planned for YEZTUGO administration once operations go live, serving patients in Mineola, Garden City, Westbury, and nearby Nassau County communities with twice-yearly PrEP planning and six-month follow-up.
View YEZTUGO site page Get directions
Manhattan
259 1st Ave, New York, NY 10003
A Manhattan site planned for YEZTUGO administration once operations go live, serving patients in StuyTown, East Village, Gramercy, and nearby Manhattan neighborhoods with twice-yearly PrEP planning and six-month follow-up.
View YEZTUGO site page Get directions
Brooklyn
308 Graham Ave, Brooklyn, NY 11211
A Brooklyn site planned for YEZTUGO administration once operations go live, serving patients in Williamsburg, Greenpoint, Bushwick, and nearby Brooklyn neighborhoods with twice-yearly PrEP planning and six-month follow-up.
View YEZTUGO site page Get directionsUse the twice-yearly access page for starter dosing, six-month scheduling, testing, and shipment timing.
Use the launch-readiness page when the real question is whether a clinic is operationally ready for YEZTUGO yet.
Use the coverage page when the blocker is prior authorization, payer routing, or Advancing Access support.
Use the sites page when the question is which NYC and Long Island clinics are the real rollout candidates once operations are live.
Use the APRETUDE lane if the patient wants the currently established long-acting PrEP path on this site while YEZTUGO readiness continues.
Use the HIV and STD testing hubs when the immediate need is testing, follow-up, or broader sexual-health support.
What patients say about Nao Medical
Verified Patient
This YEZTUGO hub was more honest than most launch pages.
Verified Patient
Helpful that it explained what operations-live actually means.
Verified Patient
The coverage and readiness sections felt practical instead of promotional.
Verified Patient
Good page for understanding how twice-yearly PrEP would actually roll out.
Verified Patient
The planned-site framing felt much more credible than pretending every location was already ready.
Verified Patient
Useful bridge page between current long-acting PrEP and the newer YEZTUGO option.
Use the readiness and planned-site pages first so the YEZTUGO rollout is understood clearly before anyone assumes immediate same-day availability.
Review launch readiness
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