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Twice-yearly YEZTUGO access in NYC

Review starter dosing, six-month continuation visits, medical-setting administration, HIV testing requirements, and the medication-shipment path before scheduling.

YEZTUGO is given as two subcutaneous injections every 6 months after starter dosing. On day 1, the patient receives two oral tablets and two injections in a medical setting. On day 2, two more oral tablets are taken at home. HIV testing is required before starting and before each injection visit.

YEZTUGO access should be clear Patients should know what needs to be confirmed before an injection visit: medication access, coverage, testing, clinic availability, and follow-up timing.

Twice-Yearly Access in plain language

YEZTUGO is given as two subcutaneous injections every 6 months after starter dosing. On day 1, the patient receives two oral tablets and two injections in a medical setting. On day 2, two more oral tablets are taken at home. HIV testing is required before starting and before each injection visit.

The medication path can slow down the first visit

YEZTUGO is not a retail-pharmacy medication. Official patient materials say the provider may carry it in office or obtain it another way, such as through a specialty pharmacy, and delivery can take about 30 days once a prescription is ordered.

What matters most here

YEZTUGO is given as two subcutaneous injections every 6 months after starter dosing. On day 1, the patient receives two oral tablets and two injections in a medical setting. On day 2, two more oral tablets are taken at home. HIV testing is required before starting and before each injection visit.

CDC recommends blood-based HIV antigen/antibody testing on the day of the initial lenacapavir injection and with follow-up injections, with HIV RNA testing at initiation if available. NYC guidance also recommends ongoing STI screening several times a year rather than assuming the six-month injection interval replaces sexual-health follow-up.

YEZTUGO is not a retail-pharmacy medication. Official patient materials say the provider may carry it in office or obtain it another way, such as through a specialty pharmacy, and delivery can take about 30 days once a prescription is ordered.

YEZTUGO locations across the network

Review address, directions, and nearby neighborhoods, then call ahead so availability and injection scheduling can be confirmed.

174th Street YEZTUGO availability and administration coordination

Bronx

174th Street

932 E 174th St, Bronx, NY 10460

A Bronx clinic that can help patients ask about YEZTUGO availability, coverage support, and PrEP follow-up, serving patients in West Farms, Crotona Park East, and nearby Bronx neighborhoods.

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Astoria YEZTUGO availability and administration coordination

Queens

Astoria

37-15 23rd Ave, Astoria, NY 11105

A Queens clinic that can help patients ask about YEZTUGO availability, coverage support, and PrEP follow-up, serving patients in Astoria, Ditmars, East Elmhurst, and nearby Queens neighborhoods.

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Bartow Mall YEZTUGO availability and administration coordination

Bronx

Bartow Mall

2063A Bartow Ave, Bronx, NY 10475

A Bronx clinic that can help patients ask about YEZTUGO availability, coverage support, and PrEP follow-up, serving patients in Co-op City, Pelham Bay, Baychester, and nearby Bronx neighborhoods.

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Crown Heights YEZTUGO availability and administration coordination

Brooklyn

Crown Heights

341 Eastern Pkwy, Brooklyn, NY 11216

A Brooklyn clinic that can help patients ask about YEZTUGO availability, coverage support, and PrEP follow-up, serving patients in Crown Heights, Prospect Heights, and nearby Brooklyn neighborhoods.

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Hicksville YEZTUGO availability and administration coordination

Long Island

Hicksville

232 W Old Country Rd, Hicksville, NY 11801

A Long Island clinic that can help patients ask about YEZTUGO availability, coverage support, and PrEP follow-up, serving patients in Hicksville, Plainview, Bethpage, and nearby Nassau County communities.

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Jackson Heights YEZTUGO availability and administration coordination

Queens

Jackson Heights

80-10 Northern Blvd, Jackson Heights, NY 11372

A Queens clinic that can help patients ask about YEZTUGO availability, coverage support, and PrEP follow-up, serving patients in Jackson Heights, Elmhurst, Corona, and nearby Queens neighborhoods.

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Jamaica YEZTUGO availability and administration coordination

Queens

Jamaica

90-18 Sutphin Blvd, Jamaica, NY 11435

A Queens clinic that can help patients ask about YEZTUGO availability, coverage support, and PrEP follow-up, serving patients in Jamaica, Briarwood, Richmond Hill, and nearby Queens neighborhoods.

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Long Island City YEZTUGO availability and administration coordination

Queens

Long Island City

30-07 36th Ave, Astoria, NY 11106

A Queens clinic that can help patients ask about YEZTUGO availability, coverage support, and PrEP follow-up, serving patients in Long Island City, Astoria, Sunnyside, and nearby Queens neighborhoods.

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Mineola YEZTUGO availability and administration coordination

Long Island

Mineola

135 Mineola Blvd, Mineola, NY 11501

A Long Island clinic that can help patients ask about YEZTUGO availability, coverage support, and PrEP follow-up, serving patients in Mineola, Garden City, Westbury, and nearby Nassau County communities.

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StuyTown YEZTUGO availability and administration coordination

Manhattan

StuyTown

259 1st Ave, New York, NY 10003

A Manhattan clinic that can help patients ask about YEZTUGO availability, coverage support, and PrEP follow-up, serving patients in StuyTown, East Village, Gramercy, and nearby Manhattan neighborhoods.

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Williamsburg YEZTUGO availability and administration coordination

Brooklyn

Williamsburg

308 Graham Ave, Brooklyn, NY 11211

A Brooklyn clinic that can help patients ask about YEZTUGO availability, coverage support, and PrEP follow-up, serving patients in Williamsburg, Greenpoint, Bushwick, and nearby Brooklyn neighborhoods.

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Helpful links for this step

Questions patients usually have

YEZTUGO is given as two subcutaneous injections every 6 months after starter dosing. On day 1, the patient receives two oral tablets and two injections in a medical setting. On day 2, two more oral tablets are taken at home. HIV testing is required before starting and before each injection visit.
CDC recommends blood-based HIV antigen/antibody testing on the day of the initial lenacapavir injection and with follow-up injections, with HIV RNA testing at initiation if available. NYC guidance also recommends ongoing STI screening several times a year rather than assuming the six-month injection interval replaces sexual-health follow-up.
YEZTUGO is not a retail-pharmacy medication. Official patient materials say the provider may carry it in office or obtain it another way, such as through a specialty pharmacy, and delivery can take about 30 days once a prescription is ordered.
Because the medication path, prior authorization, shipment, and clinic availability often have to be confirmed before the first administration visit.

200,000+ 5-star reviews

What patients say about Nao Medical

Verified Patient
(4.9)

The team walked me through the coverage and medication checks before I tried to schedule.

Verified Patient
(4.9)

The starter-dose and follow-up timing were explained in a clear way.

Verified Patient
(4.9)

I appreciated knowing that this has to be coordinated through a medical setting.

Verified Patient
(4.9)

The medication-shipment details helped me know what to ask before booking.

Verified Patient
(4.9)

It was helpful to compare twice-yearly PrEP with other options.

Verified Patient
(4.9)

The steps before an injection visit were easier to understand after calling.

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