Esketamine Nasal Spray: A New Treatment for Adolescent Depression

Depression is a serious mental health condition that affects many people, including adolescents. While there are several treatment options available, not all of them are effective or suitable for everyone. That’s why Nao Medical is excited to offer a new treatment for adolescent depression: Esketamine nasal spray.

What is Esketamine Nasal Spray?

Esketamine nasal spray is a medication that was recently approved by the US Food and Drug Administration (FDA) for the treatment of depression in adults and adolescents who have not responded to other treatments. It works by targeting a different pathway in the brain than traditional antidepressants, and it can provide rapid relief of depressive symptoms.

How Does Esketamine Nasal Spray Work?

Esketamine is a type of ketamine, which is a dissociative anesthetic that has been used in medicine for many years. However, esketamine is a different form of ketamine that is administered as a nasal spray. When used as a depression treatment, it works by blocking a specific receptor in the brain called the NMDA receptor. By doing so, it increases the levels of a neurotransmitter called glutamate, which is associated with the growth of new neural connections and the repair of damaged ones. This, in turn, can help alleviate depression symptoms.

What are the Benefits of Esketamine Nasal Spray?

Esketamine nasal spray has several benefits that make it an attractive treatment option for adolescent depression:

  • It works quickly: Some patients may experience relief of depressive symptoms within hours of the first dose.
  • It can be effective for treatment-resistant depression: Adolescents who have not responded to other treatments may benefit from esketamine nasal spray.
  • It can be used in combination with other treatments: Esketamine nasal spray can be used in conjunction with other antidepressants or psychotherapy.
  • It is convenient: Esketamine nasal spray is administered at Nao Medical’s clinic under medical supervision, and patients can return to their normal activities soon after the treatment.

How to Book an Appointment for Esketamine Nasal Spray?

If you are interested in Esketamine nasal spray as a treatment option for adolescent depression, you can book an appointment at Nao Medical’s clinic. We offer short wait times, caring staff, and a beautiful patient experience, as well as innovative technology that allows you to access all your health records through our tech platform. We also offer telemedicine and after-hours services, so you can get care when and how you need it.

To book an appointment, visit our appointment booking page and select the “Esketamine nasal spray for depression” option. Our staff will guide you through the process and answer any questions you may have.


Esketamine nasal spray is a promising new treatment option for adolescent depression that offers several benefits, including rapid relief of symptoms, effectiveness for treatment-resistant depression, and compatibility with other treatments. If you or a loved one is struggling with depression, consider booking an appointment at Nao Medical to learn more about esketamine nasal spray and other innovative and affordable healthcare services we offer.


How long does the treatment last?

The initial treatment course for esketamine nasal spray typically involves two sessions per week for four weeks, followed by one session per week for four weeks. After that, the treatment frequency may be adjusted based on the patient’s response and needs.

What are the possible side effects of esketamine nasal spray?

Some of the common side effects of esketamine nasal spray include dissociation, dizziness, nausea, and headache. However, these side effects usually resolve within a few hours after the treatment.

Does insurance cover esketamine nasal spray?

Insurance coverage for esketamine nasal spray varies depending on the plan and the patient’s condition. At Nao Medical, we accept most insurance plans and offer affordable self-pay options for patients without insurance.

Disclaimer: This blog post is for informational purposes only and should not be considered medical advice. Please consult a healthcare professional before starting any new treatment.

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Disclaimer: The information presented in this article is intended for general informational purposes only and should not be considered, construed or interpreted as legal or professional advice, guidance or opinion.

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