If you or a loved one is struggling with depression, you know how difficult it can be to find a treatment that works. Fortunately, there is hope with the latest medication called Spravato (esketamine).
Spravato is an innovative medication that was approved by the FDA in 2019 for the treatment of depression. It works by targeting the N-methyl-D-aspartate (NMDA) receptor in the brain, which has been shown to be involved in depression. Spravato is a nasal spray that is administered under the supervision of a healthcare provider.
Clinical trials are an essential part of the drug development process. They help to determine the efficacy and safety of a medication. Spravato has undergone several clinical trials to establish its efficacy and safety.
One of the most significant clinical trials for Spravato was a phase III trial called ASPIRE I and II. This trial involved over 800 patients with treatment-resistant depression. The results showed that Spravato significantly reduced depressive symptoms compared to the placebo group. This trial was the basis for the FDA’s approval of Spravato.
Another phase III trial called TRANSFORM-2 showed that Spravato was effective in reducing depressive symptoms in patients with major depressive disorder who were at imminent risk for suicide.
Research on Spravato is ongoing, and there have been several studies that have looked at its efficacy and safety. One study published in the Journal of Affective Disorders showed that Spravato was effective in reducing depressive symptoms in patients with major depressive disorder who had not responded to previous treatments.
Another study published in the Journal of Psychiatric Research looked at the safety of Spravato. The study found that Spravato was generally well-tolerated, and the most common side effects were dissociation, dizziness, and headache.
At Nao Medical
At Nao Medical, we understand how challenging it can be to find an effective treatment for depression. We offer Spravato (Esketamine) as one of our treatment options for depression. Our healthcare providers are trained in administering Spravato and monitoring patients during and after treatment.
We also offer a range of other mental health services, including counseling, therapy, and medication management. Our goal is to provide high-quality, affordable care for communities, especially in lower-income areas, and focus on preventive care.
Book an Appointment
If you or a loved one is struggling with depression, book an appointment with us today. Our caring and professional staff will help you get the care you need to feel better.
- Efficacy and safety of esketamine nasal spray for major depressive disorder: a meta-analysis of randomized controlled trials
- Esketamine nasal spray for treatment-resistant depression: a systematic review and meta-analysis of efficacy and safety
- Esketamine nasal spray in patients with treatment-resistant depression: a randomized controlled trial
- Safety and Efficacy of Esketamine Nasal Spray in the Management of Treatment-Resistant Depression
What is Spravato (Esketamine)?
Spravato (Esketamine) is a nasal spray medication that was approved by the FDA in 2019 for the treatment of depression. It works by targeting the N-methyl-D-aspartate (NMDA) receptor in the brain.
How does Spravato work?
Spravato works by targeting the N-methyl-D-aspartate (NMDA) receptor in the brain, which has been shown to be involved in depression.
Is Spravato effective for depression?
Yes, Spravato has been shown to be effective for the treatment of depression in several clinical trials.
What are the side effects of Spravato?
The most common side effects of Spravato are dissociation, dizziness, and headache.
Is Spravato covered by insurance?
Yes, Spravato is covered by most insurance plans, including Medicaid and Medicare. At Nao Medical, we accept most insurance plans, and we also offer affordable self-pay options.
How can I book an appointment for Spravato treatment?
You can book an appointment for Spravato treatment at Nao Medical by visiting our website. Our caring and professional staff will help you get the care you need to feel better.
Disclaimer: The information in this article is for informational purposes only and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Nao Medical is not responsible for any action taken by individuals based on the information provided in this article.