Common monitoring concerns

Spravato may cause sedation, dissociation, dizziness, nausea, increased blood pressure, vertigo, anxiety, vomiting, and other side effects. The care team monitors patients after dosing and checks whether they are clinically stable before leaving.

Why the REMS program exists

Spravato is restricted under a REMS program because of risks including sedation, dissociation, respiratory depression, abuse, and misuse. The certified healthcare setting requirement is designed to support safer administration and monitoring.

What to tell the care team

  • History of high blood pressure, heart disease, stroke, aneurysm, or vascular conditions.
  • Current medications, supplements, alcohol use, or sedating medications.
  • Pregnancy, plans for pregnancy, or breastfeeding.
  • History of substance-use concerns or medication misuse.
  • Side effects during prior Spravato or ketamine exposure.

Clinical references reviewed: SPRAVATO REMS and the FDA prescribing information. Last reviewed May 2026. This information does not replace a clinical evaluation.

Active Nao Medical Spravato locations

Queens

Astoria

37-15 23rd Ave, Astoria, NY 11105

A western Queens option for patients who want easier access than crossing into Manhattan for every monitored treatment day.

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Bronx

Bartow

2063A Bartow Ave, Bronx, NY 10475

A Bronx access point for patients who want local Spravato care without leaving the borough.

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Long Island

Hicksville

232 W Old Country Rd, Hicksville, NY 11801

A central Nassau option for patients who need consistent follow-up, prior auth support, and a shorter commute.

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Queens

Jamaica

90-18 Sutphin Blvd, Jamaica, NY 11435

A southeast Queens location that helps patients stay on schedule for repeated monitored sessions.

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Queens

Long Island City

30-07 36th Ave, Astoria, NY 11106

A western Queens access point for patients balancing treatment days with work, home, or Manhattan commutes.

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Long Island

Mineola

135 Mineola Blvd, Mineola, NY 11501

A Long Island access point for patients who want strong benefits support and reliable treatment coordination.

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Manhattan

StuyTown

259 1st Ave, New York, NY 10003

A Manhattan Spravato access point for East Village, Gramercy, Kips Bay, and nearby neighborhoods.

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Brooklyn

Williamsburg

308 Graham Ave, Brooklyn, NY 11211

The lead Brooklyn Spravato location for patients who want local access and ongoing psychiatric support.

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Frequently asked questions

How long am I monitored after Spravato?

Patients are monitored for at least two hours after dosing and are assessed before leaving the healthcare setting.

Can Spravato raise blood pressure?

Yes, blood pressure increases can occur. Blood pressure is reviewed as part of treatment-day safety planning.

What side effects should I report?

Report severe sedation, breathing concerns, chest pain, severe headache, confusion, worsening mood, or any symptom that feels urgent.

Can I work right after Spravato?

Patients should avoid driving, operating machinery, and high-risk activities until the next day after restful sleep.